ACE-AMCODEX   

  INJECTABLE SUSPENSION – LONG ACTING

TREATMENT OF PNEUMONIA, MASTITIS, SWOLLEN HEAD

Colistin, a cyclic poly-peptide antibiotic has bacterial action against selected Gram-negative bacteria. The primary bacterial effect of colistin is a blockade of the cell division of bacteria followed by secondary progressive lysis. Susceptible bacteria are Aerobacter aerogenes, Escherichia coli, Salmonella spp., Shigella spp., Haemophilus spp., Pasteurella spp. and Pseudomonas aeruginosa.

Amoxycillin is a semi-synthetic broad-spectrum penicillin with bactericidal action against Gram-positive and Gram-negative bacteria. The action is based on inhibition of the bacterial cell wall formation through interference of the muco-peptide synthesis. Susceptible bacteria with Amoxycillin is Streptococci, penicillinase, Staphylococci, Haemophilus spp., Corynebacterium spp., Brucella spp., Shigella spp.

The combination of Amoxycillin and Colistin together has the effect of producing a broad spectrum of antibacterial, good absorption, high concentration of  bactericidal, prolonged duration of drug to 48h.

INGREDIENTS: In 1 ml contains:

Amoxycillin trihydrate ……………………100 mg

Colistin sulfate …………………………250.000 UI

Dexamethasone acetate………. 250 mcg

INDICATIONS:

Treatment of respiratory infections, digestive tract infections, urogenital such as: Pneumonia, enteritis, diarrhea, edema disease, salmonellosis, matitis, metritis.

CONTRAINDICATIONS:

Hypersensitivity or resistance to penicillin.

DOSAGE AND ADMINISTRATION FOR USE:

Intramuscular injection:

• Cattle, Camel: 1 ml/ 12 – 15 kg body weight.
• Goat, sheep, calves: 10 – 12 kg body waight.
• Poultry: 1 ml/ 4 – 7 kg body weight.

By intramuscular (IM) injection, once dose only. The dose may be repeated after 48 hours if needed

RECOMMENDATION: Shake well the suspension before use.

DRUG INTERACTIONS:

Do not use together with bacteriostatic antibiotics including ampicillin, tetracyclines, sulfonamides. Diuretics may decrease antibiotic concentration because they accelerate ampicillin excretion. Allopurinal-like uric acid synthesis inhibitors increase skin reaction formation risk.

WITHDRAWAL PERIOD:

• For meat: 14 days.
• For milk: 3 days.

SHELF LIFE: Shown on the pack

STORAGE: Keep in shade, cool and dry place, at room temperature.

 FOR VETERINARY USE ONLY